Families of sets with locally bounded width

A family of sets ? islocally k- wide if and only if the width (as a poset ordered by inclusion) of ? is at mostk for everyx. The directed covering graph of a locally 1-wide family of sets is a forest of rooted trees. It is shown that if ? is a locallyk-wide family of subsets of {1,...,n}, then |?|≤(2k) ^k?1 n. The proof involves a counting argument based on families of closed sets associated with theSperner closures in the filters of ?. The Sperner closure ofU in ? is the intersection of the members of the greatest Sperner antichain of ? _U = {V ∈ ?|V ?U}. This closure operation is related to a generalization of maximality in posets.     

Synthesis of L-Propargylglycine and Derivatives

The chemical synthesis of L -propargylglycine (L -Pra) and of various derivatives is described. The new amino acid is a starting material for carboranylalanine (Car) and for tritiated norleucine.